Alzheimer’s Tied to Mutation Harming Immune Response

Alzheimer’s researchers and drug companies have for years concentrated on one hallmark of Alzheimer’s disease: the production of toxic shards of a protein that accumulate in plaques on the brain. But now, in a surprising coincidence, two groups of researchers working from entirely different starting points have converged on a mutated gene involved in another aspect of Alzheimer’s disease:...

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BBC Failures Show Limits of Guidelines

LONDON — It was 2004, and the British Broadcasting Corporation was gripped by a crisis over journalistic standards that had led to Parliamentary hearings, public recrimination and the resignations of its two top officials. Vowing change, the corporation established elaborate bureaucratic procedures that placed more formal responsibility for delicate decisions in the hands not of individual managers,...

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If soldier killed Afghan civilians in rampage, did he act alone?

JOINT BASE LEWIS MCCHORD, Wash. — The case against U.S. Army Staff Sgt. Robert Bales appeared at first to be horribly simple:...

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Introducing <em>Mad Science</em>, a History Book of Our Wired World

Do you know what happened on this day in 1666?You would if you read Mad Science: Einstein’s Fridge, Dewar’s Flask, Mach’s Speed, and 362 Other Inventions and Discoveries That Made Our World, the new Wired book that exposes you to the history of the ideas, creations, discoveries and events that shaped our wired world — one day at a time.Based on our popular This Day in Tech blog, and edited...

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Liza Minnelli to guest star on TV musical drama “Smash”

LOS ANGELES (Reuters) – Liza Minnelli will guest star on an episode of TV musical drama “Smash,” NBC said on Tuesday.The singer and actress will play herself and sing a number in one episode of the show when it returns in February 2013. The series, starring Debra Messing, Anjelica Huston and Katharine McPhee, dramatizes the backstage life of writers, producers...

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Recipes for Health: Roasted Eggplant and Chickpeas — Recipes for Health

Andrew Scrivani for The New York TimesEggplant is always a good, substantial vegetable to use for a vegetarian main dish. The chickpeas and the feta provide plenty of protein. Vegans can leave out the feta and substitute sugar or agave nectar for the honey.   1/4 cup extra virgin olive oil 2 garlic cloves, minced 1 28-ounce can chopped tomatoes, with juice, pulsed...

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At Microsoft, Sinofsky Seen as Smart but Abrasive

On a warm night in late October, Steven Sinofsky stood on a platform in New York’s Times Square, smiling as a huge crowd roared at the unveiling of a Microsoft retail store, where Windows 8 and the company’s new Surface tablet were about to go on sale. Less than three weeks later, Mr. Sinofsky — who, as the head of Windows, was arguably the second-most important leader at Microsoft — suddenly...

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Secret donation hindered campaigns, GOP advisors say

SACRAMENTO — An $11-million campaign donation that was secretly routed through an obscure Arizona group might have hurt the...

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A Google-a-Day Puzzle for Nov. 13

Our good friends at Google run a daily puzzle challenge and asked us to help get them out to the geeky masses. Each day’s puzzle will task your googling skills a little more, leading you to Google mastery. Each morning at 12:01 a.m. Eastern time you’ll see a new puzzle posted here.SPOILER WARNING:We leave the comments on so people can work together to find the answer....

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Australia’s INXS calls it quits as touring band after 35 years

SYDNEY (Reuters) – Australian rock group INXS has called it quits as a live touring band after 35 years, thanking fans and honoring late frontman Michael Hutchence in a statement on Tuesday.INXS, which sold more than 30 million albums worldwide, including more than 10 million alone of their 1987 breakthrough “Kick”, issued the statement after comments...

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